胸腔内灌注化疗联合热疗在癌性胸腔积液治疗中的分析

The Analysis the Treatment of Pleural Infusion Chemotherapy Combine With Hyperthermia in Treatment of Malignant Pleural Effusion

目的探究采用胸腔内灌注化疗联合热疗治疗癌性胸腔积液的临床效果。方法采用回顾性分析的方法,分析我院收治的108例癌性胸腔积液患者的临床资料,根据治疗方法的不同,随机分成对照组和实验组,各54例。对照组给予单纯胸腔内灌注化疗药物治疗,实验组给予胸腔内灌注化疗联合热疗治疗。分析比较两组患者的临床治疗有效率和不良反应情况。结果实验组的临床治疗有效率高于对照组,P<0.05,差异具有统计学意义,两组患者均没有发生恶心、头痛、骨髓抑制或肝肾功能损害等不良反应,P>0.05,差异不具有统计学意义。结论对于癌性胸腔积液患者,给予胸腔内灌注化疗联合热疗的治疗方法较好,能够明显抑制肿瘤的发生发展,提高治疗有效率,不良反应较少。

Objective To explore the clinical effect of pleural infusion chemotherapy combined with hyperthermia in the treatment of malignant pleural effusion.MethodsTo analyzed 108 cases of patients with malignant pleural effusion clinical data in our hospital, depended on the method of treatment, were randomly divided into the control group and the experimental groups, each group had 54 cases. The patients in the control group were only given the pleural infusion chemotherap, while the patients in the experimental group were treated with pleural infusion chemotherapy combined with hyperthermia. To analyzed and compare the clinical treatment efifciency and adverse reactions between the two groups. Results The clinical effective rate in experimental group was higher than the control group,P〈0.05, had difference statistically signiifcance, compared nausea, headache, bone marrow suppression or liver and kidney dysfunction and other adverse reactions,P〉0.05, had no difference statistically signiifcance. ConclusionFor patients with malignant pleural effusion, it is better to take the treatment of pleural infusion chemotherapy combined with hyperthermia. It can inhibit tumor development and improve effective rate, while fewer adverse reactions.