糖皮质激素类药物治疗结核胸膜炎56例疗效观察

Observation the Curative Effect of 56 Cases of Glucocorticoid Drugs in Treatment of Tuberculosis Pleurisy

目的通过采用糖皮质激素类药物治疗的方法对结核性胸膜炎患者进行治疗,观察其临床效果。方法将收治的56例结核性胸膜炎患者随机分成两组,各28例。A组进行常规的抗结核治疗,B组在常规抗结核治疗的基础上结合糖皮质激素类药物治疗,比较两组的治疗效果。结果 A组的总有效率78.57%,B组的总有效率为96.43%,χ2=4.081 6,P<0.05,差异具有统计学意义;两组治疗后的血清腺苷脱氨酶水平比较,P>0.05,差异不具有统计学意义,且A组的胸膜粘连率35.71%高于B组10.71%,χ2=4.908 8,P<0.05,差异具有统计学意义。结论与只采用常规抗结核治疗的效果相比,采用糖皮质激素类药物治疗的疗效更为显著。

Objective Through the use of glucocorticoid therapy method for the treatment of tuberculous pleurisy patients were observed the clinical effect.Methods Selected 56 cases of tuberculous pleurisy were randomly divided into two groups, each group had 28 cases, the group A adopt conventional anti tuberculosis treatment, the group B in the conventional anti tuberculosis therapy based on combined with glucocorticoid therapy, were compared between the two groups of treatment effect.Results The group A total effective rate was 78.57%, the group B total effective rate was 96.43%, χ2=4.0816,P〈0.05, had difference statistically significance. after treatment in the two groups of serum adenosine deaminase levels, P〉0.05, had no difference statistically significance, and the rate of a group of pleural adhesions was 35.71% higher than the group B 10.71%, χ2=4.908 8,P〈0.05, had difference significance statistically. Conclusion Compared with the effect of conventional anti tuberculosis treatment, the efifcacy of the treatment of glucocorticoid is more signiifcant, which has important clinical application value.