期刊文献+

噻托溴铵粉吸入剂治疗支气管扩张症的疗效观察 被引量:3

Clinical Observation of Tiotropium Bromide Inhalation Powder in Treatment of Bronchiectasis
下载PDF
导出
摘要 目的探讨噻托溴铵粉吸入剂治疗支气管扩张症的临床疗效。方法随机将我院收治的66例支气管扩张症患者分为两组,每组33例。对照组行常规治疗,观察组在对照组基础上行噻托溴铵治疗。比较两组FVC、FEV 1%、FEV 1/FVC等指标。结果治疗后观察组IC、FEV1、FVC、FEV 1%、FEV 1/FVC等指标优于对照组,P<0.05,差异具有统计学意义。结论噻托溴铵可改善支气管扩张症患者临床症状,降低发作次数。 Objective To explore the effect of tiotropium bromide inhalation powder in treating bronchiectasis.MethodsSelected 66 cases of patients with bronchiectasis into two groups randomly, 33 cases in each group. The control group used conventional treatment, on the basis of the control group, the observation group used thiamethoxam bromide treatment. Compare FVC, FEV 1%, FEV 1 / FVC % and other indexes of two groups. Results After treatment, the IC, FEV 1 %, FVC, FEV1, FEV 1 / FVC % and other indexes of observation group were better than the control group, P〈0.05, had difference statistically signiifcance.Conclusion The tiotropium bromide can obviously improve the clinical symptoms of patients with bronchiectasis, reduce the number of attacks.
出处 《中国继续医学教育》 2015年第26期165-166,共2页 China Continuing Medical Education
关键词 支气管扩张症 噻托溴铵 肺功能 Bronchiectasis disease Tiotropium bromide Lung function
  • 相关文献

参考文献3

二级参考文献42

  • 1慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8232
  • 2Gross NJ.Tiotropium bromide[J].Chest,2004,126(6):1946-1953.
  • 3Cui Y,Devillier P,Kuang X,et al.Tiotropium reduces lung inflam-mation in a model of chronic gastro-oesophageal reflux[J].Eur Re-spir J,2010,35(6):1370-1376.
  • 4Gerber A,Heimburg A,Reisenauer A,et al.Proteasome inhibitorsmodulate chemokine production in lung epithelial and monocyticcells[J].Eur Respir J,2004,24(1):40-48.
  • 5Pieper MP,Chaudhary NJ,Park JE.Acetylcholine induced prolifer-ation of fibroblastsand my ofibroblasts in vitrois Inhibited by tiotro-pium bromide[J].Life Sci,2007,80(24):2270-2273.
  • 6Ohta S,Oda N,Yokoe T,et al.Effect of tiotropium bromide on air-way inflammation and remodelling in a mouse model of asthma[J].Clin Exp Allergy,2010,40(8):1266-1275.
  • 7Casaburi R,Mahler DA,Jones PW,et al.A long-term evaluation ofonce daily inhaled tiotropium in chronic obstructive pulmonary dis-ease[J].Eur Respir J,2002,19(2):217-224.
  • 8Vincken W,vanNoord JA,Greefhorst A,et al.Tiotropium StudyGroup improved health outcomes in patients with COPD during oneyear treatment with tiotropium[J].Eur Respir J,2002,19(2):209-216.
  • 9Donohue JF,vanNoord JA,Bateman ED.A 6-month placebocon-trolled study comp aring lung function and health status change inCOPD patients treated with tiotro pium and salmeterol[J].Chest,2002,122(1):47-55.
  • 10Cazzola M,Noschese P,Salzillo A,et al.Bronchodilator response toformoterol After regular tiotropium or to tiotropium.after regularformoterol in COPD patients[J].Respir Med,2005,99(5):524-528.

共引文献46

同被引文献21

引证文献3

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部