奥美拉唑联合克拉霉素治疗慢性胃炎的临床疗效观察

To Observe the Clinical Curative Effect of Omeprazole and Clarithromycin in Treatment of Chronic Gastritis

目的探讨慢性胃炎患者采用奥美拉唑及克拉霉素联合治疗的临床疗效及安全性分析。方法选取我院收治的120例慢性胃炎患者,随机分为观察组和对照组,每组60例,观察组采用奥美拉唑及克拉霉素联合治疗,对照组仅采用奥美拉唑进行治疗。结果观察组的总有效率高于对照组患者,χ2=6.987 8,P<0.01,差异具有统计学意义;两组均肝、肾功能治疗前后无显著变化,均无严重不良反应发生。结论奥美拉唑及克拉霉素联合慢性胃炎患者的临床疗效优于单用奥美拉唑,且不良反应轻微,有助于加快患者的康复及提高生活质量。

Objective To explore the clinical efficacy and safety of omeprazole and clarithromycin combine treatment in patients with chronic gastritis.Methods Selected 120 patients with chronic gastritis in our hospital were randomly divided into observation group and control group, each group had 60 cases. The former uses omeprazole and clarithromycin, the latter only with omeprazole treatment.ResultsThe observation group total efficiency was higher than the control group, χ2=6.987 8,P〈0.01, had difference statistically significance. Two groups were liver and renal function before and after treatment no significant change, and had no serious adverse reactions. Conclusion The clinical efifcacy of omeprazole and clarithromycin combined with chronic gastritis patients is better than single use of omeprazole and adverse reaction of slightly, can help to speed up the rehabilitation of patients and improve the patient＇s quality of life.