摘要
目的建立柴苓降脂颗粒质量标准。方法采用TLC方法对处方中的主要药味柴胡、丹参、五味子进行薄层鉴别;采用HPLC测定其中主药白芍中芍药苷含量。结果薄层鉴别方法能检测出柴胡、丹参、五味子;有效成分芍药苷在0.125μg^1.992μg范围内线性关系良好,测定的平均回收率为99.13%,RSD为1.36%。结论所建立的方法能够对处方中的主要药味准确、快速的进行定性、定量检测,可作为柴苓降脂颗粒质量标准。
Objective: To establish the quality controlling standard for ChaiLing Jiangzhi Granule. Methods: TLC identification was conducted to identify Chaihu, Danshen and Wuweizi in the prescription; the content of paeoniflorin in Baishao the main herb in the prescription was determined by HPLC. Results: Chaihu, Danshen and Wuweizi could be detected by TCL; the linear relationship of the active components in paeoniflorin was good in the range from 0. 125 p,g tol. 992p, g, the average recovery rate and RSD were 99.13 % and 1.36 % respectively. Conclusion: The established method can accurately and rapidly conduct the qualitative and quantitative detection of the main herbs in ChaiLing Jiangzhi Granule which can be considered as the standard to control its quality.
出处
《陕西中医学院学报》
2015年第5期80-83,共4页
Journal of Shaanxi College of Traditional Chinese Medicine
基金
山西省科技攻关计划项目(20090312023)
关键词
柴苓降脂颗粒
芍药苷
薄层鉴别
含量测定
ChaiLing Jiangzhi Granule
paeoniflorin
TLC
determination of content