25羟维生素D与妊娠期高血压疾病的相关性研究被引量：11

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摘要目的探讨血清25羟维生素D水平与妊娠期高血压疾病之间的相关性。方法采用电化学发光免疫分析法检测163名妊娠期高血压疾病患者（其中A组妊娠期高血压56人、B组轻度子痫前期62人和C组重度子痫前期45人）及86名正常妊娠孕妇（对照组）在不同孕周时的血清25羟维生素D水平,分析25羟维生素D与妊娠期高血压疾病的相关性。结果在妊娠12~18周、30~36周时,对照组25羟维生素D水平为（19.2±3.14）和（23.5±2.15）ng/m L;A组为（18.6±2.35）和（20.3±2.13）ng/m L;B组为（12.4±0.34）和（17.5±1.46）ng/m L;C组为（9.6±1.45）和（11.1±2.26）ng/m L。A组与对照组的25羟维生素D水平差异无统计学意义（P〉0.05）,B、C两组25羟维生素D水平均明显低于对照组（P〈0.01）。结论 25羟维生素D的下降与子痫前期的发病相关,且早于子痫前期临床症状的出现,有预测子痫前期发生的作用。

作者周海仙吴丽群黄引平

机构地区温州市中西医结合医院(温州市儿童医院) 温州医科大学附属第一医院

出处《浙江预防医学》 2015年第10期1059-1060,1075,共3页 Zhejiang Journal of Preventive Medicine

关键词 25羟维生素D 妊娠期高血压疾病子痫前期

分类号 R714.246 [医药卫生—妇产科学]

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