摘要
目的探讨孕11~13周+6胎儿超声后大脑区域的脑部特征在诊断胎儿开放性脊柱裂中的价值。资料与方法采用经腹或经阴道超声,取125例孕11~13周+6正常胎儿和4例确诊为开放性脊柱裂胎儿,比较其颅内透明层、间脑及中脑的形态结构。结果 125例胎儿颅内透明层能清晰显示,间脑和中脑呈现"8"字形态;4例开放性脊柱裂胎儿颅内透明层消失,"8"字形态有不同程度的变形和扭曲。早孕期开放性脊柱裂胎儿的脑部因颅内负压而出现细微结构改变。结论对孕11~13周+6胎儿颅内透明层、间脑及中脑脑部特征的观察是早孕期开放性脊柱裂胎儿有价值的筛查指标。
Purpose To explore the clinical value of ultrasound in charactering brain anomalies in open spina bifida at 11-13^＋6 weeks of gestation.Materials and Methods Abdominal and transvaginal ultrasound was performed in 125 cases of normal fetus and 4 cases of confirmed open spina bifida at 11-13^＋6 weeks of gestation to compare the morphology of intracranial translucency （IT）, diencephalon and midbrain.Results Fetal IT was readily recognized in all 125 normal cases, with diencephalons and midbrain showing number ＂8＂ shape. In 4 cases of open spina bifida, fetal IT cannot be identified, and the expected ＂8＂ shape of diencephalon and midbrain was distorted.Conclusion Fetal brain characteristics including intracranial translucency and the shape of diencephalon and midbrain in 11-13＋6 weeks gestation are valuable ultrasound screening indicators for open spina bifida.
出处
《中国医学影像学杂志》
CSCD
北大核心
2015年第8期615-617,共3页
Chinese Journal of Medical Imaging
基金
广东省医学科学技术研究基金项目(C2014013)
关键词
脊柱裂
囊肿性
超声检查
产前
妊娠初期
脑
Spina bifida
cystica
Ultrasonography
prenatal
Pregnancy trimester
first
Brain
