安胃汤治疗胃溃疡随机平行对照研究

Anweitang Treat Stomach Ulcers Randomized Controlled Study

[目的]观察安胃汤治疗胃溃疡疗效。[方法]使用随机平行对照方法,将136例门诊患者按就诊顺序号法简单随机分为两组。对照组68例阿莫西林,1g/次,2次/d;克拉霉素,0.5g/次,2次/d;奥美拉唑,20g/次,2次/d;奥美拉唑维持治疗期间改为1次/d。治疗组68例安胃汤(白芍、百合各20g,丹参、制半夏、薏苡仁各15g,木香后下、乌药各7g,甘草、黄连各5g,干姜3g),1剂/d,水煎200m L,早晚口服。连续治疗42d为1疗程。观测临床症状、症状积分、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈48例,显效12例,有效7例,无效1例,总有效率98.53%。对照组痊愈36,显效15例,有效5例,无效12例,总有效率82.35%。治疗组疗效优于对照组(P<0.01)。症状、体征积分治疗组改善优于对照组(P<0.01)。[结论]安胃汤治疗胃溃疡疗效满意,无严重不良反应,值得推广。

[Objective]To observe the effect Anweitang treat stomach ulcers.[Methods]randomized,parallel controlled method,136 cases of outpatient treatment order number method is simple and randomly divided into two groups.The control group of 68 patients amoxicillin,1g/times,2 times/d;clarithromycin,0.5g/times,2 times/d;omeprazole,20g/times,2 times/d;omeprazole maintain During treatment to 1 times/d.Treatment group of 68 patients Anweitang（Baishao,Baihe 20 g,Danshen,Zhibanxia,Yiyiren 15 g,Muxiang after,Wuyao each 7g,Gancao,Huanglian 5g,Ganjiang 3g）,1 Agents/d,decoction 200 m L,sooner or later orally.42 d for a course of continuous treatment.Observation of clinical symptoms,symptom scores,adverse reactions.One course of treatment,to determine efficacy.[Results]The cure 48 cases,12 cases markedly effective in 7 cases,one case,the total efficiency of 98.53%.The control group cured 36,effective in 15 cases,5 cases,12 cases,the total efficiency of 82.35%.Treatment group than the control group（P〈0.01）.Symptoms and signs integral treatment group than the control group improved（P〈0.01）.[Conclusion]Anweitang ulcer treatment results were satisfactory,no side effects,worthy of promotion.