化痰通腑汤联合西药治疗中风急性期随机平行对照研究

Randomized Controlled Study of Acute Stroke Huatan Tongfu Soup combined with Western Medicine

[目的]观察化痰通腑汤联合西药治疗中风急性期疗效。[方法]使用随机平行对照方法,将70例住院患者按抛硬币法简单随机分为两组。对照组35例吸氧、抗感染、脱水降颅压、调控血压、营养脑细胞、营养支持及维持水电解质平衡。治疗组35例化痰通腑汤(胆南星10g,芒硝冲服6g^9g,生大黄后下10g,全瓜萎30g;头痛、项强及水肿加泽兰、川牛膝、益母草各15g;神志不清加安宫牛黄丸;热象明显加栀子12g,牡丹皮10g,黄芩12g;年老体弱津亏加生地黄、麦冬各15g;瘀血严重加桃仁10g,丹参15g,川芎10g;肝阳上亢加生龙骨30g,石决明12g,钩藤30g;语言不利加全蝎6g,石菖蒲12g;大便通畅后去芒硝;大便通畅减生大黄),1剂/d,水煎200m L,早晚分服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、神经功能缺损评分、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈14例,显效15例,有效4例,无效2例,总有效率94.29%。对照组痊愈6例,显效7例,有效14例,无效8例,总有效率77.14%。治疗组疗效优于对照组(P<0.05)。[结论]化痰通腑汤联合西药治疗中风急性期疗效满意,无严重不良反应,值得推广。

[Objective]To observe the Huatan Tongfu soup combined with western medicine treatment of acute stroke treatment.[Methods]Randomized parallel controlled method,70 patients were hospitalized method is simple coin toss randomized into two groups.The control group of 35 patients oxygen,antibiotics,dehydration reducing the intracranial pressure,blood pressure regulation,nutrition,brain cells,nutritional support and maintain water and electrolyte balance.Treatment group of 35 patients phlegm Tongfu soup（Dannanxing 10 g,Mangxiao 6g - 9g,Shengdahuang 10 g,Quangualou 30g;headache,items strong and edema Jia Zelan,Chuanniuxi,Yimucao 15g;consciousness plus unclear Angongniuhuang;hot as obvious plus Zhizi 12 g,Mudanpi 10 g,Huangqin 12g;frail Tianjin loss plus Shengdihuang,Maidong each 15g;severe bleeding plus Taoren 10 g,Danshen 15 g,Chuanxiong 10g;hyperactivity plus Shenglonggu 30 g,Shijueming 12 g,Gouteng 30g;language not american Quanxie 6g,Shichangpu 12 g,after stool to Mangxiao;stool Save Shengdahuang）;a/d,decoction 200 m L,sooner or later hours service;western medicine with the control group.14 d for a course of continuous treatment.Observation of clinical symptoms,neurological function,adverse reactions.Continuous treatment of 2 courses,to determine efficacy.[Results]The cure in 14 cases,15 cases markedly effective in 4 cases,2 cases,the total efficiency of 94.29%.6 cases were cured in the control group,7 cases were markedly effective in 14 cases,8 cases,the total efficiency of 77.14%.Treatment group than the control group（P〈0.05）.[Conclusion]Huatan Tongfu soup combined with western medicine treatment of acute stroke results were satisfactory,no side effects,worthy of promotion.