心脑动脉粥样硬化中医证型与血脂相关研究

Cardio-cerebral Atherosclerosis TCM Syndrome and Blood Lipid Research

[主要目的]分析心脑动脉粥样硬化中医证型与血脂相关性。[资料来源]选取河南新蔡县人民医院心血管内一科2010年5月至2014年5月心脑动脉粥样硬化门诊及住院患者,发放多因素调查表。[选择文献量及依据]1研究类型：问卷调查。2研究对象：1年龄42~80岁。2符合脑动脉粥样硬化及冠状动脉粥样硬化诊断标准。3辨证分型：气虚血瘀、肝肾阴虚、痰瘀互结、脾虚湿盛。4知情同意,签署知情同意书。发放问卷200份,回收190份,有效185份。[数据提炼规则及应用方法]观测证型分布、年龄、体重指数、血压、血脂。用EXCEL表建立数据库。无症状记为0,有症状记为1。采用SPSS20.0软件,计算相对频数。正态分布均数加减标准差（X±S）表示,组间比较完全随机分组均数单因素方差分析,方差不齐Dunnett检验。[数据综合得出结果与结论]证型分布：心AS气虚血瘀〉脾虚湿盛〉肝肾阴虚〉痰瘀互结,脑AS肝肾阴虚〉气虚血瘀〉脾虚湿盛、痰瘀互结,心脑AS气虚血瘀、肝肾阴虚〉痰瘀互结〉脾虚湿盛,脑心动脉粥样硬化与年龄、肥胖、高血压、高血脂密切相关（正相关）。TC、TG、HDL、LDL气虚血瘀与肝肾阴虚无显著差异（P〉0.05）,气虚血瘀与肝肾阴虚差异显著（P〈0.05）,气虚血瘀与脾虚湿盛无显著差异（P〉0.05）,肝肾阴虚与痰瘀互结差异显著（P〈0.05）,肝肾阴虚与脾虚湿盛无显著差异（P〉0.05）,痰瘀互结与脾虚湿盛差异显著（P〈0.05）。[未来展望]进一步扩大样本量,以期新突破和发展。

[The Main Purpose]Analyze cardio-cerebral atherosclerosis TCM syndrome and lipids relevance.[Source]To select the Henan Xineai County People＇s Hospital,Division of Cardiovascular in a May 2010-May 2014 cardio-cerebral atherosclerosis outpatient and inpatient,issuing multi-factor questionnaire.[Select Document Amount and Basis]（!）Type： clinical observation.Subjects：Aged 42 to 80 years old.Comply with cerebral atherosclerosis and coronary atherosclerosis diagnostic eriteria.Syndromes： blood stasis,liver and kidney,phlegm,spleen dampness.Informed consent,informed consent.[Data Mining Rules and Application Methods]Observation syndrome distribution,age,body mass index,blood pressure,blood lipids,Establishment of a database table with EXCEL.Asymptomatic denoted by 0,1 recorded as symptomatic.Using SPSS 20.0 software to calculate the relative frequency.Normal mean plus or minus standard deviation（X±S ）that the group completely randomized ANOVA mean,variance missing Dunnett test.[Data integration Outcome and Conclusions]Syndrome Distribution：Heart AS QDBS〉Spleen dampness〉liver and kidney〉phlegm,brain and liver and kidney AS 〉QDBS〉SpIeen wet Sheng,phlegm each node,cardiovascular AS blood stasis,liver and kidney〉phlegm〉 Spleen wet Sheng,brain heart atherosclerosis associated with age,obesity,hypertension,high cholesterol（positive correlation）.TC,TG,HDL,LDL and liver and kidney Qi and Blood was no significant difference（P〉0.05）,and liver and kidney Qi and Blood significantly different（P〈0.05）,Qi and Blood Sheng no significant difference between wet spleen（P〉0.05）,liver and kidney with phlegm significant difference（e〈0.05）,liver and kidney and spleen Sheng no significant difference between wet（P〉0.05）,phlegm and dampness spleen was significantly different（P〈0.05）. [Future]Need to further expand the sample size,in order to have a new breakthrough and development.