活血安神方足浴治疗维持性血液透析不安腿综合征随机平行对照研究

Syndrome Randomized Controlled Study Huoxue Anshen Soup Foot Sedative Maintenance Hemodialysis Patients with Treatment of Restless Leg

[目的]观察活血安神方足浴治疗维持性血液透析不安腿综合征疗效。[方法]使用随机平行对照方法,将50例住院患者按就诊顺序号法简单随机分为两组。对照组25例左卡尼汀,10~20mg/kg,1次/d,静注;维生素B12,0.025~0.1mg/次,1次/d,肌注;叶酸,5~10mg/次,2次/d。治疗组25例活血安神方（丹参、黄芪、白芍、牡蛎、龙骨、桑白皮、鸡血藤各30g,茯苓、百合、夜交藤、酸枣仁各20g,黄连、知母、生地、黄柏、玄参各15g,川芎10g）,1剂/d,水煎100m L,1次/d。连续治疗14d为1疗程。观测临床症状、RLS评分、睡眠质量评分、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈12例,显效8例,有效4例,无效1例,总有效率96.00%。对照组痊愈6例,显效10例,有效2例,无效7例,总有效率72.00%。治疗组疗效优于对照组（P〈0.05）。评分指标两组均有改善（P〈0.01）,治疗组改善优于对照组（P〈0.01）。[结论]活血安神方足浴治疗维持性血液透析不安腿综合征疗效满意,无严重不良反应,值得推广。

[Objective]To observe the treatment of promoting blood circulation and soothe the nerves square foot maintenance hemodialysis patients restless leg syndrome.[Methods]Randomized parallel controlled method,50 eases of hospitalized patients with treatment order number method is simple and randomly divided into two groups.The control group of 25 patients with left-earnitine,a dose of 10-20mg/kg, 1 times/ d,intravenous;vitamin B12,0.025-0. lmg/times, 1 times/d,intramuseular injeetion;folie acid,5-10mg/times ,2 times/d.Huoxue treatment group,25 eases of sedative side（Danshen,Huangqi,Baishao,Muli,Longgu,Sanghaip i,Jixueteng 30g,Fuling,Baihe,Yejiaoteng,Suanzaoren each 20g,Huanglian,Zhimu,Shengdi,Huangbai,Xuansh en 15g,Chuanxiong 10g）,l/d,decoction 100mL,1 times/d.14d for a course of continuous treatment.Observation of clinical symptoms,RLS score,sleep quality score,adverse reactions.One course of treatment,to determine effieaey.[Results]The cure 12 eases,8 eases were markedly effective in 4 eases,1 ease,the total efficiency of 96.00%.6 eases were cured in the control group, 10 eases markedly effective in 2 eases,7 eases,the total efficiency of 72.00%.Treatment group than the control group（P〈0.05）.Rating indicators improved in both groups （P〈0.01）,the treatment group than the control group improved（P〈O.O1）.[Conclusion]Blood soothe the nerves square foot patients undergoing maintenance hemodialysis treatment of restless legs syndrome satisfactory,no side effects,worthy of promotion.