杭州地区不同妊娠期孕妇微量元素检测分析

Detection and analysis of Hangzhou pregnant women's microelements during various gestation periods

目的分析杭州地区不同妊娠期孕妇微量元素水平变化,为孕妇合理补充微量元素提供临床指导。方法按孕周将813例孕妇分为早孕组（〈12周）、中孕组（12周～28周）和晚孕组（〉28周）,同时选取83例健康未孕育妇女作为对照组,采用原子吸收光谱法分别测定全血中铁、锌、钙、镁、铜、铅的浓度水平。结果在早孕期、中孕期孕妇全血中铜、铁及镁含量明显降低（P〈0.05）,在晚孕期含量则明显升高（P〈0.01）;孕妇在中孕期、晚孕期全血钙含量明显低于对照组（P〈0.01）;全血锌在孕妇早孕期、中孕期含量明显低于对照组（P〈0.01）。全血铅孕期组明显低于对照组（P〈0.01）。结论杭州地区妊娠期孕妇不同孕期微量元素含量存在着一定差异,妊娠妇女应定期进行微量元素的检测,并根据不同孕周,合理补充微量元素,以保证母体和胎儿双方的需求,提高优生优育。

Objective To analyze microelement variations of Hangzhou pregnant women during different gestation periods, and provide clinical guidance on supplementing microelements for pregnant women. Methods According to gestation periods, 813 pregnant women were divided into early pregnancy group （ 〈 12 weeks）, midterm pregnancy group （12 weeks -28 weeks） and late pregnancy group （ 〉 28 weeks） ; 83 healthy non -pregnant women were selected as a control group for comparison ; atomic absorption spectroscopy was adopted to measure the concentration levels of iron, zinc, calcium, magnesium, cuprum and plum- bum of whole blood. Results The levels of cuprum, iron and magnesium of whole blood showed a significant decline （P 〈 0.05） during early and midterm pregnancy, and a significant rise （P 〈0.01 ） during late pregnancy. During midterm and late pregnancy the level of calcium in whole blood was significantly lower than that of the control group （ P 〈 0.01 ）. During early and midterm pregnancy the level of zinc in whole blood was significantly lower than that of the control group （ P 〈 0.01 ）. During all pregnancy the level of plumbum in whole blood was significantly lower than that of the control group （P 〈 0.01 ）. Conclu- sion There are variations in the levels of microelements during different gestations of Hangzhou pregnant women, who therefore should have their microelements detected on a regular basis, and should supple microelements according to gestational weeks, so as to meet the maternal and fetal demands and ensure a healthy pregnancy.