沈阳市2013年-2014年流感监测结果分析

A study on the influenza surveillance results in Shenyang during 2013-2014

目的通过对2013年-2014年沈阳市流感监测结果进行分析,了解流感流行规律,为制定流感防控措施提供依据。方法采集全市哨点医院和暴发疫情的流感样病例数据和样本,对病原学的监测结果资料进行整理分析。结果2013年-2014年沈阳市流感样病例占就诊病例的4.75%。全市哨点医院共采集流感样病例咽拭标本1 321份,流感病毒核酸检测阳性率为20.06%,分离到135株流感病毒,分离率为50.94%。其中甲型H1N1型71株(52.59%)、B型(Yamagata系)51株(37.78%)、季节性流感H3N2型13株(9.62%)。全市报告流感疫情2起,均为B型流感暴发,其中1起为B型混合感染。结论 2013年-2014年沈阳市流感活动高峰后移,核酸检测结果更能准确地反映流感流行情况,流感毒株对MDCK细胞系敏感度下降。

Objective To study the results of influenza surveillance in Shenyang during 2013 -2014, to explore the pattern of influenza circulation, so as to provide basis for the measures making for influenza control and prevention. Methods To select the data and specimen from influenza- like illness（ILI） in the guarding hospitals and outbreak areas, and to regulate and ana- lyze the pathologic surveillance results. Results The ILI attendance rate in outpatients and emergency patients was 4.75% from 2013 to 2014. From the guarding hospitals in Shenyang a total of 1 321 swab samples were collected with RNA - positive percent of 20.06% and 135 strains were isolated, and the separation rate was 50.94%, consisting of 71 strains of A/H1N1 subtype（52.59% ）, 51 strains of type B Yamagata -lineage（37.78% ） and 13 strains of seasonal H3N2 subtype （9.62%）. A total of 2 outbreaks were reported and both were tested positive for influenza of type B, of which 1 outbreak was co - infected with type B. Conclusion The epidemical peak seasons of influenza in Shenyang from 2013 to 2014 were later than usual. Nu- cleic acid test results can more accurately reflect the influenza epidemic situation. And the sensitivity of the influenza viral strains to the MDCK cell line decreased.