替扎尼定治疗三叉神经痛有效性及安全性评析

Tizanidine Treatment Effectiveness and Safety of Trigeminal Neuralgia

目的：分析替扎尼定治疗三叉神经痛有效性及安全性。方法将2012年2月~2015年3月收治于我院的三叉神经痛患者94例为研究对象，采用电脑分组法将其均分成观察组47例以及对照组47例。其中观察组患者采用替扎尼定治疗；对照组患者采用卡马西平治疗。对比分析两组患者的治疗效果以及安全性。结果经过不同的治疗方式后，观察组患者21例痊愈、14例显效、10例有效、2例无效，治疗总有效率为95.7%（45/47）；对照组患者10例痊愈、13例显效、14例有效、10例无效，治疗总有效率为78.7%（37/47）；观察组患者治疗效果明显优于对照组（P＜0.05），两组间比较差异显著。结论针对于三叉神经痛患者而言，在治疗过程中选择采用替扎尼定具有令人满意的治疗效果，同时替扎尼定耐受性较好。

ObjectiveTo analyze the tizanidine treatment efficacy and safety of trigeminal neuralgia.Methods94 patients with trigeminal neuralgia were treated in our hospital from February March to 2012, 47 cases of the observation group and 47 cases in control group were divided into observation group and control group with cases. The observation group were treated with Tizanidine treatment; the control group was treated with C Masi Bing therapy. Comparison and analysis of the two groups of patients with treatment efficacy and safety. Results After different treatment, the observation group of patients 21 cases cured, 14 cases markedly effective, 10 cases effective, 2 cases ineffective, the total effective rate was 95.7% （45/47）; the control group of patients with 10 cases, 13 cases were effective, 10 cases ineffective, the total effective rate was 78.7% （37/47）; the treatment effect of the observation group was significantly better than the control group （P〈0.05）, the difference was significant between the two groups.Conclusion Needle for patients with trigeminal neuralgia, in the course of treatment choice use of tizanidine has satisfactory therapeutic effect, and tizanidine was well tolerated.