超前使用氟比洛芬酯对人工流产术后子宫收缩痛的作用

Postoperative Analgesia Effects on Uterine Contraction Pain by Early Use of Flurbiprofen Axetil in Artificial Abortion Patients

目的:探讨超前使用氟比洛芬酯对人工流产术后子宫收缩痛的镇痛作用。方法:采用单中心、随机对照的方法,纳入ASAⅠ–Ⅱ级需要行人工流产术患者100例,随机分为试验组和对照组。试验组经静脉先给予氟比洛芬酯1mg/kg,对照组经静脉给予生理盐水10ml。两组均在5分钟后给予丙泊酚2.5mg/kg。评价两组在术后苏醒5、15、25、35分钟子宫收缩痛的VAS评分。结果:试验组在苏醒后5、15、25和35分钟的VAS评分均低于对照组,组间差异有统计学意义(P<0.01)。与术后苏醒5分钟相比,两组均在在苏醒后15分钟子宫收缩痛VAS评分明显降低。结论:人工流产术前给予氟比洛芬酯能有效抑制术后子宫收缩痛,并缩短疼痛持续时间。

Objective： To observe postoperative analgesia effects on uterine contraction pain by early use of flurbiprofen axetil in artificial abortion patients. Methods： This was a single center, randomized and controlled study. A total of 100 ASA I or II artificial abortion patients were enrolled to treatment group or control group in the ratio of 1：1. Treatment group were administered intravenously to flurbiprofen axetil lmg/kg, control group received normal saline （10ml） intravenously. Five minutes later both groups were given the propofol （2.Smg/kg）. The uterine contractions pain VAS scores were evaluated at 5, 15, 25 and 35 minutes after surgery awake respectively. Resaflts： VAS scores of treatment group at 5, 15, 25 and 35 minutes after surgery awake were significantly lower than that of the control group （P〈0.01）. Compared with 5 minutes after surgery awake, VAS scores of both groups decreased significantly at 15 minutes. Conclusions： The early use of flurbiprofen axetil in artificial abortion patients could effectively reduce uterine contractions pain and shorten the duration of pain.