老年急性脑梗死患者脑动脉狭窄的分布及其危险因素研究

Risk Factors and Characteristics of Distribution of Cerebral Artery Stenosis in Elderly Patients with Acute Cerebral Infarction

目的:探讨老年急性脑梗死患者脑动脉狭窄的分布及其危险因素。方法:对150例老年急性脑梗死患者及144例对照组人群进行经颅多普勒超声和血压、血脂、血糖、吸烟饮酒史、心脑血管病家族史进行收集。结果:研究组颅内动脉狭窄检出率(42.0%)高于对照组(13.9%)(P<0.05),颅内动脉狭窄分布为MCA 41.3%、TICA 31.7%、VA 14.3%、ACA 9.5%、BA 6.3%、PCA4.8%。血脂异常、长期吸烟、长期饮酒、高血压、糖尿病、心脑血管病家族史、胆红素、尿酸以及C反应蛋白与颅内动脉狭窄相关。结论:关注颅内动脉狭窄及其危险因素对老年急性脑梗死患者非常重要,控制危险因素是医务工作者的重要工作。

Objective： To investigate the risk factors and characteristics of distribution of cerebral artery stenosis in elderly patients with acute cerebral infarction. Methods： One hundred and fifty elderly patients with acute cerebral infarction were evaluated by TCD compared with the control group. The risk factors include blood pressure, blood sugar and cholesterol. Results： The frequency of stenosis of the study group（42.0%） was higher than that of the control group（13.9%）. The distribution of cerebral artery stenosis was MCA41.3%, TICA 31.7%, VA 14.3%, ACA 9.5%, BA 6.3% and PCA 4.8%. Dyslipidemia, long-term smoking, long-term alcohol consumption, hypertension, diabetes, and family history of cardiovascular disease were related with intracranial artery stenosis.Conclusion： Monitoring intracranial arterial stenosis and risk factors is very important for elderly patients with acute cerebral infarction.Controlling the risk factors is significant for physicians.