喷昔洛韦乳膏联合卡介菌多糖核酸注射液治疗面部扁平疣患者的疗效观察

To observe the Curative effect of Penciclovir Cream combined BCG Polysaccharide and Nucleic Acid Injection Treatment of Facial Flat wart Patients

目的探讨喷昔洛韦乳膏联合卡介菌多糖核酸注射液治疗面部扁平疣患者的疗效。方法选取2012年8月至2013年9月医院门诊皮肤科收治的100例面部扁平疣患者资料,根据1:1配对方法将其分为对照组和观察组,各50例。对照组患者给予卡介菌多糖核酸注射液治疗,观察组患者在对照组基础上外涂喷昔洛韦乳膏,比较两组患者的治疗效果及不良反应发生情况。结果观察组患者治疗第1个疗程、第2个疗程总有效率均明显高于对照组,差异均有统计学意义(均P<0.05);两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论采用喷昔洛韦乳膏联合卡介菌多糖核酸注射液治疗面部扁平疣患者,可明显提高临床疗效,安全可靠。

Objective To investigate the clinical effect of Penciclovir Cream combined BCG Polysaccharide and Nucleic Acid Injection treating facial verruca plana.Methods From August 2012 to September 2013,100 patients with facial warts were divided into control group and observation group according to 1：1 matching method,and 50 cases were treated with the method of observation.While the control group were intramuscularly card BCG polysaccharide nucleic acid in treatment,the observation group patients in the control group based outer coating of penciclovir cream,were compared between the two groups of treatment effect,adverse reaction incidence.Results The observation group of patients with the first course of treatment,the two treatment the total effective rate of the therapy were significantly higher than that of the control group,differences were statistically significant（P〈0.05）.The adverse reactions of two groups of patients occurred rate difference was not statistically significant（P〉0.05）. Conclusion The penciclovir cream combined with BCG polysaccharide nucleic acid injection in the treatment of facial flat warts can significantly improve the clinical efficacy,safety and reliability.