期刊文献+

原发性肝癌发生机制及其治疗的研究进展 被引量:46

原文传递
导出
摘要 目的:了解原发性肝癌的发生机制及其治疗的研究进展。方法:查阅近年来国内外相关文献,对原发性肝癌的发病机制、诊断与分期及治疗的研究进展进行归纳、总结。结果:原发性肝癌发病机制复杂,组织病理学、细胞分子生物学以及影像学检测手段均被用来诊断早期肝癌,治疗方案应根据原发性肝癌分期来选择。结论:原发性肝癌的发病机制复杂,早期诊断困难,需实行个性化治疗并努力寻找多靶点药物的联合应用。
出处 《中国药房》 CAS 北大核心 2015年第29期4171-4173,共3页 China Pharmacy
  • 相关文献

参考文献24

  • 1White DL,Kanwal F,El-Serag HB.Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer,based on systematic review[J].Clin Gastroenterol Hepatol,2012,10(12):1 342.
  • 2Fattovich G,Stroffolini T,Zagni I,et al.Hepatocellular carcinoma in cirrhosis:incidence and risk factors[J].Gastroenterology,2004,127(5):35.
  • 3Chen G,Lin W,Shen F,et al.Past HBV viral load as predictor of mortality and morbidity from HCC and chronic liver disease in a prospective study[J].Am J Gastroenterol,2006,101(8):1 797.
  • 4Lee MH,Yang HI,Lu SN,et al.Hepatitis C virus seromarkers and subsequent risk of hepatocellular carcinoma:long-term predictors from a community-based cohort study[J].J Clin Oncol,2010,28(30):4 587.
  • 5Tian S,Hui X,Fan Z,et al.Suppression of hepatocellular carcinoma proliferation and hepatitis B surface antigen secretion with interferon-λ1 or PEG-interferon-λ1[J].FASEB J,2014,28(8),3 528.
  • 6Boyd A,Gozlan J,Maylin S,et al.Persistent viremia in HIV hepatitis B coinfected patients undergoing long-term tenofovir:virological and clinical implications[J].Hepatology,2014,60(2),497.
  • 7Bruix J,Sherman M.Management of hepatocellular carcinoma:An update[J].AASLD Practice Guidelines,2010,53(3):1 020.
  • 8王阁,张志敏.肝癌发生机制的探索以及分子靶向治疗的契机与挑战[J].世界华人消化杂志,2013,21(19):1791-1796. 被引量:6
  • 9Zhao M,He HW,Sun HX,et al.Dual knockdown of Nras and epiregulin synergistically suppressed the growth of human hepatoma cells[J].Biochem Biophys Res Commun,2009,387(2):239.
  • 10Jeon YE,Lee SC,Paik SS,et al Histology-directed matrix-assisted laser desorption/ionization analysis reveals tissue origin and p53 status of primary liver cancers[J].Pathol Int,2011,61(8):449.

二级参考文献64

共引文献89

同被引文献544

引证文献46

二级引证文献233

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部