活化白细胞黏附分子基因siRNA腺病毒载体构建及其体内外抑制肝癌作用
Antitumor activity of siRNAs targeting ALCAM in HepG2 liver cancer cells in vitro and in vivo
摘要
活化白细胞黏附分子(ALCAM)为免疫球蛋白基因超家族成员,存在于人体各组织器官的跨膜糖蛋白中。ALCAM为I型跨膜蛋白,通过异嗜性黏附形式和同嗜性黏附形式介导细胞间黏附脚。有研究结果显示,
出处
《中华肝脏病杂志》
CAS
CSCD
北大核心
2015年第10期781-783,共3页
Chinese Journal of Hepatology
基金
重庆市自然科学基金项目(2011BB5123)
关键词
腺病手毒科
肝肿瘤
活化白细胞黏附分子
Adenoviridae
Liver neoplasms
Activatedleukocyte celladhesion molecule
参考文献18
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