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氮杂糖类免疫抑制剂的研究进展 被引量:1

Recent advances in iminosugars as immunosuppressants
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摘要 氮杂糖作为最重要的糖模拟物之一具有多种重要的生物活性和潜在的应用价值。本文就近年来氮杂糖类免疫抑制剂的研究进行综述,主要从合成方法和免疫抑制活性评价两方面进行介绍。 Iminosugars,as an extremely interesting and versatile class of carbohydrate mimics,possess various biological activities and application value. This review w ill describe the recent advances in the field of iminosugars as immunosuppressive agents,and both chemical and biological aspects concerning their preparation and / or occurrence in nature as w ell as their immunosuppressive properties w ill be discussed.
出处 《中国药物化学杂志》 CAS CSCD 2015年第5期397-406,共10页 Chinese Journal of Medicinal Chemistry
基金 国家自然科学基金重大研究计划项目(91213301)
关键词 氮杂糖 免疫抑制 化学合成 构效关系 iminosugar immunosuppressant chemical synthesis structure-activity relationships
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