运动、高血压与血管内皮细胞生长因子研究进展

Research Progress on Exercise,Hypertension and Vascular Endothelial Growth Factor

高血压已经在全世界范畴内成为影响国民健康的重大公共卫生问题,也是最常见的慢性疾病,且致残﹑致死率极高。高血压疾病不仅与胰岛素抵抗有关,还与血管内皮细胞及代谢障碍有关,如何安全有效的在高血压早期通过内皮功能障碍及血管壁的损伤与重塑来改善高血压是很有意义的。运动可以改善高血压引起的血管损伤,其可能机制与运动时VEGF表达增加有关。所以,关于运动、高血压与血管损害之间的研究具有重要意义。

Hypertension has become the great public health problem affecting people′s health in the whole world, and is also the most common chronic disease and disability,and death rate is extremely high. Hypertensive diseases associated with insulin resistance and vascular endothelial cells and associated metabolic disorders,how safe and ef-fective in the early stage of hypertension through endothelial dysfunction and vascular wall damage and reconstruc-tion to improve hypertension is very meaningful. Exercise can improve hypertension-induced vascular injury and its possible mechanisms and associated with increased VEGF expression during exercise. So in terms of movement,be-tween study on hypertension and vascular damage is significant.