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SDF-1/CXCR4轴及其对老年血管新生的影响机制进展 被引量：3

SDF-1/CXCR4 axis and its mechanisms of impact on angiogenesis in the old
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摘要 心血管疾病是老年人常见的慢性病,严重威胁着老年人的身体健康,随着老龄化问题的日益突出,心血管疾病的治疗越来越受到医学界的重视。基质细胞衍生因子-1(Stromal cell-derived factor-1,SDF-l)及其受体CXCR4轴在诱导自体骨髓源细胞(Bone marrow-derived cells,BMCs)进行血管修复和新生血管再生过程中发挥了重要的促进作用。本文就SDF-1/CXCR4轴信号传导通路的组成及其在血管新生中的作用以及与老年人血管生成反应丧失相关性进行综述。
作者 胡惠琼 吴雄伟 杨玉燕 曾宪智 郑永霞
机构地区 嘉兴学院医学院
出处 《四川生理科学杂志》 2015年第3期137-139,共3页 Sichuan Journal of Physiological Sciences
基金 嘉兴学院大学生研究训练(SRT)计划项目 嘉兴市科技计划项目(编号:2012AY1075-11) 浙江省大学生科技创新活动计划(新苗人才计划)项目 嘉兴学院大学生科研计划项目(编号:SRT2014B117)
关键词 SDF-1/CXCR4 骨髓细胞 血管新生 老年
分类号 R54 [医药卫生—心血管疾病]
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  • 1蓝艳.补阳还五汤对气虚血瘀型缺血性脑卒中患者血浆基质金属蛋白酶影响[J].福建中医药,2013,44(1):21-22. 被引量：18
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四川生理科学杂志
2015年 第3期

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