小儿急性扁桃体炎非细菌病原体IgM抗体检测结果分析

Analysis on IgM antibody test results of non-bacterial pathogens in children acute tonsillitis

目的了解小儿急性扁桃体炎非细菌性感染病原体情况,为临床合理选用抗微生物治疗药物提供依据。方法采用间接免疫荧光法检测220例急性扁桃体炎患儿血清标本中的非细菌病原体IgM抗体。结果 220例标本中,检出非细菌病原体抗体阳性标本98例,阳性检出率44.54%;共检出非细菌病原体抗体146例次,其中肺炎支原体47例次、腺病毒9例次、乙型流感病毒72例次、副流感病毒18例次。有40例标本同时检出2种及2种以上非细菌病原体抗体,检出率40.82%(40/98)。联合检出率最高的非细菌病原体抗体组合是乙型流感病毒抗体+肺炎支原体抗体。结论呼吸道非细菌病原体抗体检测对小儿急性扁桃体炎非细菌病原体感染的诊断和治疗具有指导意义。

Objective To understand the non‐bacterial infection pathogens situation in children acute tonsillitis to provide the basis for clinical rational use of antimicrobial drugs .Methods The indirect immunofluorescence（IFA） method was adopted to detect IgM antibody of non‐bacterial pathogens in serum specimens from 200 children patients with acute tonsillitis .Results Among 220 specimens ,98 cases were detected antibody positive of non‐bacterial patho‐gens ,the positive detection rate was 44 .54% ;146 case‐times of non‐bacterial pathogen antibodies were detected ,in which 47 case‐times were mycoplasma pneumoniae ,9 case‐times were adenovirus ,72 case‐times were influenza B and 18 case‐times were parainfluenza virus .2 kinds or over 2 kinds of non‐bacterial pathogens were simultaneously detec‐ted in 40 cases of specimen ,the detection rate was 40 .82% ,（40/98） .The highest detection rate of non‐bacterial pathogen combination was influenza B antibody plus mycoplasma pneumoniae antibody .Conclusion The antibody detection of respiratory tract non‐bacterial pathogens has the guidance significance to the diagnosis and treatment of children acute tonsillitis .