氧杂蒽二酮合成条件探索

Exploring the Synthetic Conditions of Xanthenedione

以苯甲醛和1,3-环己二酮为原料,以乙醇为溶剂,采用常规合成方法、无溶剂研磨法和微波法3种方法合成氧杂蒽二酮,最高收率分别为69%、50%和75%。对3种方法进行对比分析发现,微波法产率高,操作简便。微波法中苯甲醛和环己二酮的摩尔比为1∶2,微波功率为230 W,反应时间为15min。

Synthesis of xanthenedione is presented with benzaldehyde and 1,3-- cyclohexanedione as raw material, by the conventional synthesis method using ethanol as solvent, solvent-free grinding method and microwave irradiation method. The yield could reach 69%,50% and 75%, respectively. The three methods are compared and analyzed. The microwave irradiation method exhibits higher yield, shorter reaction time without solvent and catalyst. The reaction conditions is the molar ratio of benzaldehyde and cyclohexanedione= 1 ： 2, microwave power 230W, reaction time 15rain.