平阳霉素与^32P胶体混合局部注射治疗黏液囊肿的疗效分析

A clinical study on the treatment of mucocele by bleomyin A5 combined with phosphorus-32 colloid

目的 探讨平阳霉素^＋32P胶体局部注射治疗黏液囊肿的疗效.方法将 2010年1月至2012年12月在兰州大学第二医院口腔门诊及核医学科门诊就诊的214例黏液囊肿患者按照局部注射药物不同分为3组：平阳霉素组（50例）、32P胶体组（50例）、平阳霉素^＋32P胶体组（114例）,3组在黏液囊肿局部注射药物后观察疗效.疗效标准：治愈、基本治愈、有效和无效.用xx检验3组的有效率.结果 治疗有效率：平阳霉素组84％ （42/50）、32p胶体组82％（41/50）、平阳霉素^＋32P胶体组98％（112/114）.3种方法治疗黏液囊肿均有效（P＜ 0.05）,平阳霉素组与32p胶体组差异无统计学意义（P＞0.05）,平阳霉素^＋32P胶体组治疗效果优于二者单独使用,差异均有统计学意义（P＜0.05）,减少了单独使用的并发症.结论 平阳霉素^＋32P胶体局部注射治疗黏液囊肿简便易行、疗效显著、痛苦小、安全可靠、并发症少,费用低.

Objective To evaluate the effect of bleomyin A5 combined with phosphorus-32 colloid in the treatment of mucocele.Methods A total of 214 patients divided into three groups,bleomyin A5（50 cases）,phosphorus-32 colloid（50 cases） and bleomyin A5 combined with phosphorus-32 colloid（114 cases）.Results The efficacy of bleomyin A5 group,phosphorus-32 colloid group,and bleomyin A5 combined with phosphorus-32 colloid group was 84% （42/50）,82% （41/50） and 98% （112/114）,respectively.There were significant difference in efficacy among the three groups （P〈0.05）.The phosphorus-32 colloid group and the bleomyin A5 group had no significant difference in efficacy（P〉0.05）.Conclusions The independent use of bleomyin A5 and phosphorus-32 colloid is effective,but the combined use of the two methods is more effective.