摘要
长链非编码RNA(IncRNA)是一类不具有编码蛋白质功能的RNA,长度超过200个核苷酸。近年来,随着筛选技术的进步,越来越多的IncRNA被发现,IncRNA的研究结果提示其在肝脏疾病的发生、发展过程中起到关键性的作用。本文着重就IncRNA在肝脏疾病中的研究现状作以阐述。
Long non-coding RNAs(IncRNAs) are a group of RNAs which have no protein-coding function and are longer than 200 nt. In recent years, with advances in triage techniques, more and more IncRNAs are found. Results show that lncRNAs play a key role in liver diseases, especially in tumorigene- sis,metastasis and prognosis. This article reviews recent advancements in research on IncRNAs in order to better understand the role of lncRNAs in the process of liver disease.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2015年第10期2330-2332,共3页
Chinese Journal of Experimental Surgery
基金
国家自然科学基金资助项目(81470876、81270527)
黑龙江省自然科学科学基金(QC2013C094)