胸腺类癌脊柱转移一例报告

Thymic carcinoid with spine metastasis: 1 case report

胸腺类癌（thymic carcinoid）于1972年由Rosai等[1]首次命名,起源于胸腺内的Kulchitzky细胞,属于神经内分泌癌,其发生率约占全部胸腺肿瘤的2%-5%[2],属较罕见疾病。胸腺类癌缺乏典型临床症状,常见症状包括胸闷、胸痛、胸部不适、憋气、咳嗽、咳痰等,部分患者完全没有临床症状,仅在查体时发现胸腺肿物。

Objective To report 1 patient diagnosed as thymic carcinoid with spine metastasis. Methods A 56-year-old man had pain in the neck and right shoulder for 1 year. Pain aggravated in nearly 1 month. Cervical MRI showed multiple abnormal signals and C2 soft-tissue mass intruding into the vertebral canal. Cervical vertebrae CT scan showed multiple bone erosion. The diagnosis of thymic carcinoid was acquired by preoperative cervical lymph node biopsy and histopathological examination. The patient underwent cervical laminectomy, internal fixation and occipitocervical fusion. Results Significant alleviation of the pain in the neck and shoulder was achieved. The postoperative histological examination confirmed the diagnosis of thymic carcinoid. Conclusions Thymic carcinoid with spine metastasis is a rare disease. Posterior laminectomy, vertebroplasty plus internal fixation is an effective method in the treatment of thymic carcinoid with spine metastasis.