甘露醇在重症急性胰腺炎治疗中的应用

Application of Mannitol in the Treatment of Severe Acute Pancreatitis

目的探讨甘露醇在重症急性胰腺炎治疗中的使用。方法 90例重症急性胰腺炎患者随机分为观察组与对照组两组,每组45例。对照组行常规治疗,观察组在常规治疗的基础上加用甘露醇治疗。结果观察组腹胀缓解的时间,肠鸣音恢复时间,血,尿淀粉酶恢复时间,体温、白细胞计数恢复时间,均较对照组明显缩短(P<0.05),观察组平均住院日、病死率与对照组比较亦有显著性差异(P<0.05)。结论重症急性胰腺炎治疗中,加用甘露醇治疗可以明显缩短腹胀缓解时间、肠鸣音恢复时间、恢复排便排气时间,明显减少患者的平均住院日、病死率。

Objective To investigate the clinical efficacy of mannitol in the treatment of severe acute pancreatitis. Method 80 cases of severe acute pancreatitis patients were randomly divided into observation group and control group, each group of 40 cases. The control group was given conventional treatment, the observation group in the conventional therapy plus treatment with magnesum sulfate. Result The observation group abdominal distension relieving time, the recovery time of bowel sound, bloodamylase urine amylase recover time, body temperature, white blood cell count recovery time, were significantly shorter than the control goup（p〈0.05）. In observation group, the average hospital day, mortality compared with the control group also had significant difference（p〈0.05）. Conclusion The treatment of severe acute pancreatitis, combined with mannitol treatment can significantly shorten the abdominal distension relieving time, the recovery time of bowel sound, recovery of exaust defeacation time. Singnificantly reduce te average lenge of stay of patients, mortality.