脑卒中后便秘的中医证型及多因素分析

Analysis of TCM syndrome type and multiple factors for patient with constipation after stroke

目的:探讨脑卒中后便秘的中医证型及分析相关因素,提高预防的针对性和有效性。方法:对100例脑卒中后患者分为便秘组68例、无便秘组32例,根据《慢性便秘中医诊疗共识意见》进行中医证型统计,采集人口学因素(性别、年龄、民族、婚姻等)、发病前排便情况、饮食方式、脑卒中类型和部位、治疗用药情况等35项指标,进行单因素优势比(OR)分析和多因素Logistic回归分析。结果:中医证型以肺脾气虚型比例最高,单因素分析显示女性、高龄、出血性脑卒中、基底神经节区病变、应用抗抑郁药患者便秘多发率较高,Logistic分析显示性别、年龄、卒中类型、治疗中应用抗抑郁药为便秘的独立相关因素。结论:脑卒中后便秘中医证型以肺脾气虚型多见,性别、年龄、卒中类型、治疗中应用抗抑郁药是影响便秘的独立因素,临床用药治疗要考虑上述因素。

Objective： To investigate the TCM syndrome type in constipation after stroke and the related factors in order to improve the pertinence and effectiveness of prevention. Methods： TCM Syndromes of chronic constipation for 100 cases of post-stroke patients with habitual constipation of after TCM diagnosis and treatment according to the statistics of ＂consensus＂ is analyzed and their t their demographic factors（gender, age, nationality, marriage, etc.） before the onset of defecation, diet, stroke type and position, treatment of 35 indicators, univariate odds ratio（OR） is collected and logistic analysis and multi factor regression analysis is done. Results： the TCM syndrome type of lung and spleen deficiency type occupy the highest proportion, the single factor analysis showed that age, female, hemorrhagic stroke, basal ganglia lesions, application of antidepressants in patients with constipation multiple rate is higher, Logistic analysis showed that gender, age, type of stroke, the treatment using antidepressants were independent factors for constipation. Conclusion： Stroke prone to constipation, lung and spleen deficiency of TCM. Application of antidepressant drugs, sex, age, type of stroke treatment were independent factors influencing constipation.