摘要
溶解素基序(LysM)是一类普遍存在于大多数有机体中的蛋白质结构域。植物细胞中含有LysM结构域的蛋白能够识别不同种类含有N-乙酰葡糖胺结构的配体分子,从而启动植物对病原菌的特异防御反应。作为一种重要的模式识别受体,LysM结构域蛋白通过不同形式的寡聚化、受体类胞质激酶BIK1和MAPK级联反应向下游传递信号,而病原菌能够通过其分泌的效应蛋白特异性识别或修饰模式识别受体,规避植物细胞中病原体相关分子模式诱导的免疫反应。该文主要综述受体激酶/蛋白在病原菌激发子识别和防卫反应启动中的作用。
Lysin motif(LysM) is a ubiquitous protein domain found in most living organisms.LysM-containing proteins in plant cells can recognize different GIcNAc-containing ligands,thereby triggering specific defense responses to pathogens.As a group of important pattern recognition receptors,LysM-containing proteins trigger downstream signaling by oligomerization,thus interacting with the Botrytis-induced kinase 1(BIK1) and mitogen-activated protein kinase(MAPK)cascade.Pathogenic microorganisms also use certain mechanisms to escape from pathogen-associated molecular pattern-triggered immunity by utilizing specific recognition or modification of pattern recognition receptors by the secreted effector proteins.This review focuses on the functions of these receptor kinases/proteins in response to elicitor stimuli and priming of defense responses.
出处
《植物学报》
CAS
CSCD
北大核心
2015年第5期628-636,共9页
Chinese Bulletin of Botany
基金
国家重点基础研究发展计划(No.2013CB127103)
国家自然科学基金(No.31300249
No.31000092
关键词
防卫反应
免疫
溶解素基序
病原菌
defense responses
immunity
Lysin motif
pathogenic bacteria