肠易激综合征患者焦虑、抑郁及其睡眠障碍调查分析

Investigation analysis on psychological status and somnipathy of irritable bowel syndrome patients

目的探讨肠易激综合征（IBS）患者的焦虑、抑郁及睡眠等特征，揭示其内在的关系。方法选择45例IBS患者为病例组，同时随机选择45例健康体检者为对照组，采用焦虑量表（SAS）、抑郁量表（SDS）、匹兹堡睡眠质量指数量表（PSQI）对两组研究对象进行调查，比较两组患者的焦虑、抑郁、睡眠障碍发生率，以及睡眠质量评分。结果IBS组的焦虑、抑郁、睡眠障碍发生率分别为28．9％、40．O％、48．9％，均明显高于对照组的8．9％、11．1％、17．8％（P〈0．05）；IBS组的睡眠质量、日间功能障碍、睡眠障碍、安眠药物等因子评分均明显高于对照组（P〈0．01），而IBS组的入睡时间、睡眠时间及睡眠效率等因子评分与对照组相比差别无统计学意义（P〉0．05）。结论IBS患者存在较为严重的焦虑、抑郁、睡眠障碍，而且IBS组的整体睡眠质量比健康人群差，临床治疗过程中应进行综合干预。

Objective To explore the characteristics of anxiety, depression and sleep of irritable bowel syndrome （IBS） patients, and reveal its intrinsic relationship. Methods 45 IBS patients were chose as case group and 45 healthy people were chosen through health examination as control group. With self rating anxiety scale （ SAS）, self-rating depressive scale （SDS） and pittsburgh sleep quality index scale （PSQI）, we investigated She two subjects, and then compared the incidence rates of anx- iety, depression and somnipathy, and scores of sleep quality between the two groups. Results The incidence rates of anxiety, depression and somnipathy in the IBS group were respectively 28.9%, 40.0% and 48.9% , all much bigger than those of the control group （ respectively 8.9%, 11.1% and 17.8%, all P〈0. 05）. Scores of sleep quality, daytime dysfunction, somnipathy and sleeping pills in the IBS group were much higher than those of the control group （P〈0. 01 ）, but there were no statistical sig- nificance about the time falling asleep, bed time and sleep efficiency between the two groups （P〉0.05）. Conclusion IBS pa- tients had fairly severe anxiety, depression and somnipathy, and their total sleep quality was worse than healthy population. So we should carry out comprehensive intervention measures in clinical treatment.