摘要
用GPAT试验盒在197例单用DDS的麻风治愈者中进行了调查,并对比了使用血清法和干血法所得的结果,发现两者的一致率达88％,其阳性率分别为27.9％和36.5％;此两法所用的滴度一致率为80％,相差一个滴度的占13％,相差两个滴度的为6％。在599例治愈者中用GPAT和PGL—ELISA对照,发现前者的特异性和敏感性分别为94.3％和93.9％。在GPAT阳性的治愈者中,原为MB的,其复发率为9.6％;原为PB的,其复发率为4.5％;GPAT阴性者则无一复发。每例试验用干血系采20μl耳血制成,折合血清8μl,但因挤压时含有一些组织液,故稀释液以加108μl为最好。
A comparison of GPATs by the use of sera and dried bleed on filter paper was made in 197 cases of lep- rosy who had cured with only DDS. The results showed that the coincidence rate between the both is 88％, and the positive rate is 27.9％ in the former and 36.5％ in the latter. The coincidence rate of the titers in the two methods is 80％, but the differences between the both with one titer is 13％ and with two tiler is 6％. The controlling survey between GPAT and PGL—ELISA in 599 cases of leprosy cured only with DDS showed that the specificity and sensitivity of GPAT are 94.3％ and 93.9％ respectively. Among the cures with positive GPAT the relapse rate was 9.6％ in original MB, and 4.5％ in original PB, but among those with negative GPAT there was no relapse found. The dried blood is made from 20μl of ear lobe blood, amounting to 8μl of the serum, but because of the pressure of the sampling it might contain a few tissue fluid, and therefore it is better to add only 108μl of the diluent to it.
