体外冲击波治疗ⅢB型前列腺炎疗效的Meta分析

Efficacy of extracorporeal shock wave therapy on chronic prostatitis ⅢB: Meta-analysis

目的：评价体外冲击波治疗（extracorporeal shock wave therapy，ESWT）治疗ⅢB型前列腺炎的临床有效性，并对临床文献进行质量评价。方法：检索1996年1月至2015年5月中国知网（National Knowledge Infrastructure，CNKI）、万方、PubMed、EMbase、Cochrane Library数据库中有ESWT治疗ⅢB型前列腺炎对照研究的RCT文献，根据纳入和排出标准，筛选合适文献，并用RevMan 5.1软件进行统计分析。结果：共有8篇文献符合纳入标准，共计592例患者，其中治疗组323例，对照组269例。ESWT治疗ⅢB型前列腺炎的总有效率显著高于对照组（OR=18.32，95% CI：4.13-81.33，Z=3.82， P=0.0001）。二者治疗后症状积分相比，差异有显著性，（WMD=–5.08，95% CI：–6.89-–3.28， Z=5.52，P〈0.00001）。结论：ESWT治疗ⅢB型前列腺炎的疗效确切，是治疗ⅢB型前列腺炎的有效方法之一。

Objective：To assess the effcacy of extracorporeal shock wave therapy （ESWT） on chronic prostatitisⅢB, and evaluate the quality of the literatures. Methods：We retrieved all the case-control studies on ESWT for chronic prostatitisⅢB between January 1996 to May 2015 in National Knowledge Infrastructure （CNKI）, Wanfang Data, PubMed, EMbase, and Cochrane database, screened the eligible literature according to the selection and exclusion criteria, and performed meta-analyses of the included studies with the software Revman 5.1. Results：Eight eligible reports were identiifed in this study, including 323 cases and 269 controls. Meta-analysis showed a signiifcant difference on overall effectiveness between the ESWT and control groups （OR=18.32, 95%CI：4.13~81.33, Z=3.82, P=0.0001）. Also, there is a significant difference of symptom score between the two groups （WMD=–5.08, 95%CI：–6.89~–3.28, Z=5.52, P〈0.00001）. Conclusion：ESWT exhibited a deifnite effect for the treatment of chronic prostatitisⅢB.