肺炎支原体感染与高血压患者的血清流行病学关系研究

Investigation on the serum epidemiological relationship between Mycoplasma pneumoniae infection and hypertension

目的探讨肺炎支原体感染与高血压患者的血清流行病学关系,为临床提供预防和治疗依据。方法选择2013年3月-2015年3月医院接诊的80例患者进行研究,根据其是否患高血压分为高血压组和非高血压组各40例,使用Seroidia-Mycoll颗粒凝集试剂盒检测血清中的MPIgG抗体,使用SPSS18.0软件进行统计分析。结果高血压组患者肺炎支原体(MP)感染40例,感染率100.00%,显著高于非高血压组患者感染率50.00%,差异有统计学意义(P<0.05);高血压组患者年龄≥50岁、男性患者例数、吸烟、高血脂、体质量指数(BMI)、腰臀比(WHR)各项指标均高于非高血压组,差异有统计学意义(P<0.05);肺炎支原体感染和性别、血脂异常、超高体质量对于高血压均具有正相加模型的交互作用,在影响因素未调整之前以上中两者交互作用而导致的高血压患病危险性分别是1.92、1.7201和1.24,以上两者同时存在时,患高血压危险性有28.00%、28.00%和25.00%是交互作用所致;在对影响因素分别作出调整以后,危险性分别是7.006、4.455和0.477,以上两者同时存在时,患高血压危险性有50.00%、45.00%和15.00%是交互作用所致。结论肺炎支原体感染和高血压有关联,并且还和高血压的其他因素存在交互作用。

OBJECTIVE To study the serum epidemiological relationship between Mycoplasma pneumoniae infection and high blood pressure ,so as to provide the basis for the prevention and treatment of hypertension .METHODS Totally 80 cases from Mar .2013 to Mar .2015 were studied .According to the presence of hypertension ,patients were divided into the hypertension group and the non‐hypertension group ,40 cases in each group .The Seroidia‐Mycoll method was used to detect MPIgG antibodies in sera and the SPSS18 .0 software was used for statistical a‐nalysis .RESULTS The hypertension group had 40 cases of M .pneumoniae （MP） infection ,the infection rate was as high as 100 .00% ,significantly higher than 50 .00% in the non‐hypertensive infection （P〈0 .05） .Indexes such as the number of patients ≥50 years of age ,the number of male patients ,smoking ,high cholesterol rate ,body mass index （BMI） and waist‐hip ratio （WHR） in the hypertension group were all significantly higher than those in the non‐hypertensive group （P〈0 .05） .M .pneumoniae infection and gender ,dyslipidemia ,overweight ,and high blood pressure had a positive additive model of interaction .Risk of high blood pressure was 1 .92 ,1 .7201 and 1 . 24 for the interaction of the above each two factors before adjustment of the above factors and 28% ,28% and 25%of the risk of suffering from high blood pressure were caused by the interaction at the co‐existence of two factors . After making adjustments of each factor separately ,the risk was 7 .006 ,4 .455 and 0 .477 respectively .At the co‐existence of two above factors ,50 .00% ,45 .00% and 15 .00% of the risk of suffering from high blood pressure were caused by the interaction .CONCLUSION M .pneumonia infection and hypertension is related ,and there is in‐teraction with other factors of hypertension .