菊糖面包对STZ糖尿病小鼠血脂、血糖的影响

Effect of inulin bread on blood glucose and lipid of mice with diabetes induced by STZ

用链脲佐菌素(STZ)诱导成功的糖尿病小鼠为动物实验模型,将小鼠分为模型组、普通面包组、各种不同添加量(2%、4%、6%、8%、10%)的菊糖面包组,连续喂食15 d,研究血糖、总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、体重的变化情况。结果表明,菊糖能够缓解STZ糖尿病小鼠体重的下降,降低STZ糖尿病小鼠的血糖值,并且对高脂血症有一定的调节作用,同时随着菊糖面包中菊糖含量的增加,其作用效果也得到增强。

As animal models,diabetic mice were successfully induced by using the STZ. These mice divided into model group,ordinary bread group,variety of different amounts of inulin bread group（2%,4%,6%,8%, 10%）, feeded 15 days ,studied the changes of blood glucose,total cholesterol ,triglycerides, HDL, LDL, body mass. The results showed that the inulin could alleviate weight drops of STZ diabetic mice,lowered blood glucose levels in STZ diabetic mice,and had a certain adjustment of hyperlipidemia. At the same time,with the increase of the inulin content in the bread ,the effect was improved.