老年性癫癎的研究进展
摘要
癫癎是一种常见且严重的神经系统疾病,主要是脑部神经元发生异常性放电导致突然、反复、短暂的中枢神经系统功能异常,属于一种短暂性脑功能失调综合征。老年性癫癎是指患者65岁及以上发病的癫癎类型。在此类人群中,癫癎发病率约为134/10万,其患病率约为1.5%,是青年癫癎患病率的2倍。流行病学研究显示,老年人癫癎的发生率明显高于其他年龄组,且发病风险随着年龄增长而增加。
出处
《癫痫与神经电生理学杂志》
2015年第5期296-299,共4页
Journal of Epileptology and Electroneurophysiology(China)
参考文献27
-
1Stefan H. Epilepsy in the elderly: diagnostic and therapeutic problems[J]. MMW Fortsehr Med, 2006 2 : 88-90.
-
2Elizabeth 2M, Willim DF. Status epilepticus in the elderly: differential diagnosis and treatment[J]. Neuropsychiatric Dis Treat, 2011,7 161-166.
-
3Huang Y, Guo J, Wang Q, et al. MicroRNA-132 silencing de- creases the spontaneous recurrent seizures[J]. Int J Clin ]xp Med,2014,7 : 1639-1649.
-
4Wallace H, Shorvon SD, Tallis R. Age-specific incidence and prevalence rates of treated epilepsy in an unselected population of 2 052 922 and age-specific fertility rate of women with epi- lepsy[J]. Lancet, 1998,352 : 1790-1793.
-
5Lossius MI, Ronning OM, Schlapo GD. Poststroke Epilepsie: occurrence and predictors-a longterm prospective controlled study(Akershus stroke stfldy) [J]. Epilepsia, 2005,46 : 1246- 1257.
-
6Burneo JG, Fang J, Saposnik G (for the investigators of the Registry of the Canadian Stroke network). Impact of seizures on morbidity and mortality after stroke:a Canadian multicen- tre cohort study[J]. Eur J Neurol, 2010,17 : 52-58.
-
7Burn J, Dennis M, Bamford J, et al. Epileptic seizures after a first stroke project[J]. Br Med J, 1997,315 1582-1587.
-
8Benbir G, Ince B, Dozluolcay M. The epidemiology of posts- troke epilepsia according to stroke subtypes[J]. Acta Neurol Scand,2006,114z8-12.
-
9Bladin CF, Alexandrov AV, Bellavance A, et al. Seizures after stroke. A prospective multieenter study [J]. Arch Neurol, 2000,57 : 1617-1622.
-
10Lamy C,Domigo V,Semah F,et al. Early and late seizures af- ter cryptogenic ischemic stroke in young adults[J]. Neurolo- gy, 2003,60 : 400-404.
二级参考文献13
-
1白素梅,庞月同,李建华.脑卒中后癫痫76例临床分析[J].山东医药,2007,47(13):87-88. 被引量:10
-
2Faught E,Richman J,Martin R,et al. Incidence and prevalence of epilepsy among older US Medicare beneficiaries[J]. Neurology, 2012,78(2) :448-453.
-
3Rishi V,Peter P. Epileptic fits and epilepsy in the elderly:General refections,specific issues and the rapeuticimplications[J]. Clin Neurol Neurosurg, 2007,109 (9) : 727-743.
-
4Forsgren L,Beghi E,Oun A,et al. The epidemiology of epilepsy in Europe-a systematic review[J]. Eur J Neurol,2005,12(3): 245-253.
-
5Kwan P, Arzimanoglou A,Berg A, et al. Hippoeampal tan pathology is related to neuroanatomical connections:an ageing population- based study[J]. Brain,2009,132(5) : 1324-1334.
-
6Hermann B,Seidenberg M,Sager M,et al. Growing old with epilepsy:the neglected issue of eognitive and brain health in ag- ing and elder persons with chronic epilepsy[J]. Epilepsia,2008,49 (5) :731-740.
-
7Bernardi S,Sealdaferri N,Vanacore N,et al. Seizures in Alzheimer's disease:a retrospective study of a cohort of outpatients [J]. Epileptic Disord, 2010,12( 1 ) : 16-21.
-
8Michael C,Shelia J,Feng H,et al. Incidence of new-onset seizures in mild to moderate Alzheimer disease[J]. Arch Neurol, 2012,69(3) : 368-372.
-
9Brodie MJ,Stephen LJ. Outcomes in elderly patients with newly diagnosed and treated epilepsy [J]. Int Rev Neurobiol,2007,81 ( 1 ) : 253-263.
-
10卢蕾,王赞,孟红梅,崔俐,吕玉丹,林卫红.以抽搐发作为首发症状的234例老年癫痫的病因及临床特点分析[J].中风与神经疾病杂志,2010,27(2):164-166. 被引量:9
共引文献4
-
1王双艳,秦琴保,王敏健,于小琪,李晴.高龄继发性癫痫患者的临床分析[J].中国医学创新,2015,12(13):139-142. 被引量:1
-
2欧楚耿.嗅沟脑膜瘤的显微外科手术治疗预后分析[J].中国医学创新,2015,12(13):142-145.
-
3刘莎莎,吕洋.老年人新发癫痫临床分析[J].中华老年医学杂志,2018,37(3):268-271. 被引量:6
-
4刘涛,兰春伟,袁昆雄,王清勇,薛立军.老年部分性发作癫痫持续状态的临床特征及视频脑电图分析[J].中国医药导报,2019,16(16):95-99. 被引量:3
-
1郭章玉,崔元孝.脑电图在抗癫痫药物治疗中应用的研究进展[J].山东医药,2012,52(13):96-98. 被引量:14
-
2王有国.如何紧急处理小儿癫痫发作[J].求医问药,2007(1):28-29.
-
3覃从军,廖峻,吴春华,唐芹.脑卒中继发癫痫48例的临床分析[J].内科,2009,4(6):950-951. 被引量:1
-
4曾丽,郑金瓯,宋少霞.重症肌无力体感诱发电位的研究[J].脑与神经疾病杂志,2003,11(2):106-107. 被引量:2
-
5何洁华,孙美群.睫状神经营养因子在癫痫发病机制中的研究进展[J].蚌埠医学院学报,2014,39(10):1446-1449.
-
6钟伟锋.胼胝体发育不良1例报告[J].基层医学论坛,2009,13(2):95-95.
-
7董斌,周农,汪凯.癫患者认知障碍的发病机制[J].中华神经科杂志,2006,39(10):705-706. 被引量:11
-
8梁文能,雷进.颞叶内侧癫痫的伽玛刀治疗[J].四川医学,2010,31(12):1873-1876. 被引量:1
-
9孙敏娟.进行性肌营养不良的神经电图的检查分析[J].实用医技杂志,2005,12(02B):472-473.
-
10黄燕红.癫痫住院患者70例的护理[J].中国误诊学杂志,2010,10(2):428-428. 被引量:3