静脉用人血丙种球蛋白治疗儿童重症毛细支气管炎的临床效果

Clinical efficacy analysis of intravenous gamma globulin treatment of human blood in the severe bronchiolitis

目的观察静脉用人血丙种球蛋白治疗重症毛细支气管炎患儿的疗效。方法选取2013年11月~2014年10月收治的重症毛细支气管炎患儿68例,将其随机分为观察组和对照组,每组34例。对两组患儿均采取综合治疗,在此基础上,观察组联合人血丙种球蛋白治疗。观察两组患儿的临床病情症状和生命体征,统计患儿肺部哮鸣音消失的时间、呼吸困难消失的时间、咳嗽消失的时间以及住院天数。结果观察组重症毛细支气管炎患儿的肺部哮鸣音消失的时间、呼吸困难消失的时间、咳嗽消失的时间、住院天数均少于对照组,组间差异均具统计学意义（P〈0.05）;观察组总有效率为94.12%,对照组总有效率为76.47%,差异具有统计学意义（P〈0.05）。结论使用人血丙种球蛋白治疗儿童重症毛细支气管炎,可获得显著的治疗效果。

Objective To observe the clinical efficacy of intravenous gamma globulin treatment of human blood in the Severe bronchiolitis. Methods 68 cases of patients with severe bronchiolitis from November 2013 to October 2014 in our hospital were selected and randomly divided into two groups, 34 cases in each group. The two groups have taken comprehensive treatment, and observation group of patients were joint human gamma globulin treatment on the basis of complex treatment, then observe the clinical symptoms and vital signs of the disease, the lungs of children with wheeze statistical vanishing time, difficulty breathing time disappear, cough disappeared time, length of hospital stay. Results Lungs wheeze observation group of children with severe bronchiolitis disappearance of time, difficulty breathing time to disappear, cough disappeared time, length of hospital stay were less than the control group（P〈0.05）; the total effective rate of the observation group was higher than that of the control group（P〈0.05）, the difference was statistically significant, the total effective rate of the observation group was 94.12%, and the control group was 76.47%.Conclusion Using human gamma globulin in the treatment of children with severe bronchiolitis, can obtain significant therapeutic effect.