溴化亚铜催化合成二甲亚砜叶立德的新方法

Copper(Ⅰ) Bromide-Catalyzed for the Synthesis of Sulfoxonium Ylides

一个简单高效地制备二甲亚砜叶立德的方法已经被发展起来,该方法以重氮化合物为原料,在二甲亚砜溶剂中反应.值得注意的是,该方法使用了廉价低毒的溴化亚铜作为催化剂,并且该方法反应体系温和、官能团兼容性好、产率高,这将使该方法有着不错的应用前景.

A simple and efficient method for the synthesis of substituted sulfoxonium ylides from diazocompounds in dimethyl sulfoxide was developed. It is notable that the reaction employs cheap and harmless copper（I） bromide as catalyst. Moreover, the mild reaction system and a wide range of substrates with high yields make the protocol very practical.