摘要
目的：建立低硼硅玻璃安瓿包装盐酸戊乙奎醚注射液中硅迁移量的测定方法。方法：采用石墨炉原子吸收分光光度法测定硅的迁移量。结果：硅在0-85 ng·ml-1浓度范围与吸光度呈良好的线性关系（r=0.995 6）,平均加样回收率为95.85%,RSD为4.60%（n=9）。结论：该方法灵敏、快速、准确,重复性好,可用于低硼硅玻璃安瓿包装盐酸戊乙奎醚注射液中硅迁移量的测定。
Objective：To establish a method for the determination of Si migration in penehyclidine hydrochloride injection packed with low borosilicate glass ampoule. Methods： Si migration was determined by graphite furnace-atomic absorption spectrometry. Re-sults：The linear concentration range was 0-85 ng·ml-1（r=0. 995 6）. The average recovery was 95. 85% and RSD was 4. 60% （n=9）. Conclusion：The method is sensitive, rapid and accurate with good repeatability, which can be used to determine Si migration in penehyclidine hydrochloride injection packed with low borosilicate glass ampoule.
出处
《中国药师》
CAS
2015年第10期1693-1694,共2页
China Pharmacist
关键词
低硼硅玻璃安瓿
盐酸戊乙奎醚注射液
硅
迁移量
Low borosilicate glass ampoule
Penehyclidine hydrochloride injection
Si
Migration
