重度卵巢过度刺激综合征患者妊娠结局

Pregnancy outcome of patients with severe ovarian hyperstimulation syndrome

卵巢过度刺激综合征（Ovarian hyperstimulation syndrome,OHSS）是一种发生于应用促排卵药物后的具有潜在生命威胁的严重并发症,其中重度OHSS的发生率约为0.5%~5%。为了减少或避免严重并发症的发生,目前大部分OHSS相关研究都着力于OHSS的预防及治疗策略上,而临床妊娠结局则被放在了相对次要的方面。与OHSS相伴随的血流动力学失稳定、血液浓缩以及一些中间介质可能影响其妊娠结局。关于OHSS妊娠结局的临床研究较少,结果也有一定的争议。本文综述重度OHSS妊娠后围植入期、围产期等相关妊娠结局,探讨OHSS妊娠后安全性。

Ovarian hyperstimulation syndrome（OHSS）is a serious and potentially life-threatening complication after over-stimulating ovary.An overall reported incidence of severe OHSS is 0.5% to 5%.Till now,much effort has been made to prevent it,and the anticipated pregnancy naturally becomes of secondary importance.The hemodynamic destabilization and hemoconcentration accompanied with OHSS and some intermediate media may affect pregnancy outcomes.There are many publications on OHSS,but few on its impact on pregnancy outcomes.The pregnancy outcome in peri-implantational and perinatal in the patients with severe OHSS are described and analyzed in this paper to evaluate the pregnancy security after severe OHSS.