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湿地真菌Talaromyces flavus中2个新的聚酯类化合物 被引量：4

Two new polyesters from wetland soil-derived fungus Talaromyces flavus
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摘要 从一株蓝状菌属真菌Talaromyces flavus(No.BYD07-13)固体发酵物中分离得到了2个聚酯类新化合物talapolyesters G^H(1~2),采用质谱和核磁共振谱确定了它们的结构。化合物1~2的绝对构型是通过碱水解确定。对化合物1~2还评价对5株肿瘤细胞(HL-60,SMMC-7721,A-549,MCF-7,SW480)的生长抑制活性。 Two new polyesters,talapolyesters G-H（ 1-2） were isolated from the wetland soil-derived fungus Talaromyces flavus BYD07-13,and their structures were determined by NMR and MS spectroscopic data. The absolute configurations of the residues were determined by alkaline hydrolysis. The cytotoxicity against five tumor cell lines（ HL-60,SMMC-7721,A-549,MCF-7 and SW480） of1-2 was examined.
作者 何军伟 高昊 刘杏忠 姚新生
机构地区 暨南大学药学院中药及天然药物研究所 江西中医药大学中药资源与民族药研究中心 中国科学院微生物研究所真菌学国家重点实验室
出处 《中国中药杂志》 CAS CSCD 北大核心 2015年第17期3347-3351,共5页 China Journal of Chinese Materia Medica
基金 国家自然科学基金项目(81422054)
关键词 湿地真菌 黄蓝状菌 talapolyesters G^H 细胞毒活性 wetland soil-derived fungus Talaromyces flavus talapolyerters G-H cytotoxicity
分类号 R284 [医药卫生—中药学]
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参考文献16

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中国中药杂志
2015年 第17期

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