1550 nm非剥脱点阵激光治疗痤疮瘢痕的疗效观察

Efficacy of non-ablative 1550-nm fractional laser on acne scars

目的 评估1550 nm非剥脱点阵激光对痤疮瘢痕、痤疮红斑的疗效及其相关因素,为提高疗效提供依据.方法 回顾性分析2011年12月至2013年6月于北京协和医院皮肤激光中心进行1550 nm非剥脱点阵激光治疗痤疮瘢痕、痤疮红斑的27例患者.采用四级法对疗效进行评估.结果 1550 nm非剥脱点阵激光对痤疮瘢痕、痤疮红斑的有效率分别为13.0％（3/23）和44.0％（11/25）;患者的性别、年龄、病期等与疗效无相关性,而治疗次数与痤疮红斑疗效呈正相关（r=0.619,P＜0.05）.治疗中未发现任何严重的不良反应.结论 1550 nm非剥脱点阵激光可能成为治疗部分痤疮性瘢痕、痤疮性红斑等患者的有效方法.

Objective To evaluate the clinical efficacy of the non-ablative 1550 nm fractional laser on post-acne atrophic scarring and post-acne erythema.By following up,the correlative factors were analyzed to guide the further use of the non-ablative 1550 nm fractional laser.Methods Twentyseven patients who received the non-ablative 1550 nm fractional laser therapy from Dec.2011 to June 2013 were enrolled in this retrospective study.We used a quartile grading scale for evaluation of postacne atrophic scarring and post-acne erythema.Results The effective rate was 13.0％ （3/23） for post-acne atrophic scarring and 44.0％ （11/25） for post-acne erythema.Nonparametric test showed that there was no statistical correlation of the efficacy with gender,age and courses of disease.But there was positive correlation between efficacy and treatment frequencies on post-acne erythema （r=0.619,P＜0.05）.No severe adverse effect was observed.Conclusions We suggest that the nonablative 1550 nm fractional laser may provide a new treatment algorithm in some cases of post-acne atrophic scar and post-acne erythema.