摘要
目的:探讨D-二聚体检测对结肠癌患者的临床意义。方法:随机选择2012年12月-2014年12月我院收治的50例结肠癌患者为观察组,选择同期的50例健康体检者为对照组,检测两组人群的D-二聚体水平。研究发生转移的结肠癌和未发生转移结肠癌患者之间的D-二聚体水平的差异和临床分期与D-二聚体含量之间的关系。结果:观察组中D-二聚体检测阳性率为52.00%,而对照组检出率为0,组间比较,差异有统计学意义(P<0.05)。转移性结肠癌患者的D-二聚体水平显著高于未发生转移结肠癌患者(P<0.05)。结肠癌Ⅱ、Ⅲ、Ⅳ期患者的D-二聚体水平依次递增,各分期间具有显著性差异(P<0.05)。结论:D-二聚体水平与结肠癌患者病情相关,病情越严重,D-二聚体水平越高。
Objective To study the meaning of the level of D dimer in patients with colon cancer. Method Fifty patients with colon cancer which my hospital treated were selected random as observation group. In the meantime, 50 health examination clients were selected as control group. The level of D dimer was determined for investigating the difference between two groups. Besides, the concentration of D dimer was determined between control group with metastasis and without metastasis. At last, the relationship between D dimer r and clinical stage was analyzed. Result The positive rate of the observation group was 52.00 %, while it was 0 in control group, showing significant difference（P 0.05）. The concentration of D dimer for patients with metastasis was higher than the patients in control group without metastasis. The concentration of D dimer r increased sequentially in order of stage Ⅱ、Ⅲ、Ⅳ of colon cancer. Conclusion The concentration of D dimer can suggest the state of illness in patients with colon cancer. The concentration of D dimer is applicable for assessing patients＇ condition.
出处
《深圳中西医结合杂志》
2015年第18期14-16,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
