摘要
目的探讨氯氮平治疗难治性精神分裂症的效果。方法选取88例难治性精神分裂症患者,随机分为实验组与对照组,每组44例,给予对照组利培酮治疗,给予实验组在利培酮治疗基础上使用氯氮平治疗,观察两组患者的治疗效果。结果实验组患者治疗总有效率为93.2%,对照组患者总有效率为79.5%;治疗后实验组患者的PANSS评分明显低于对照组,对比差异显著(P<0.05),具有统计学意义。结论针对难治性精神分裂症患者,使用氯氮平治疗,可以有效地提高治疗效果,减轻患者的临床症状,提高生活质量,值得推广使用。
Objective Discuss the effect of clozapine treatment of refractory schizophrenia.Methods Select 88 cases of patients with treatment-resistant schizophrenia, randomly divided into experimental group and control group, each group of 44 cases, control group risperidone was given to the experimental group on the basis of risperidone therapy using clozapine treatment, to observe the therapeutic effect of two groups of patients.Results Experimental treatment in patients with total effective rate 93.2%, control group total effective rate was 79.5%; The experimental group after treatment in patients with PANSS score significantly lower than the control group, compared to significant difference ( P<0.05 ) , with statistical significance.Conclusion For treatment -resistant schizophrenia patients, the use of clozapine treatment, can effectively improve the treatment effect, reduce the patient's clinical symptoms, improve quality of life, is worth promoting.
出处
《广东微量元素科学》
CAS
2015年第10期57-59,共3页
Trace Elements Science
