探讨重型肝炎患者并肺部真菌感染的易感因素及防治措施

Predisposing factors and preventive measures of pulmonary fungal infection in patients with severe hepatitis

目的:探讨重型肝炎患者并肺部真菌感染的易感因素及防治措施.方法:选取重型肝炎并肺部真菌感染患者48例作为观察组,重型肝炎无肺部真菌感染患者70例作为对照组,对两组糖皮质激素、抗生素和侵袭性操作应用情况进行观察.结果:观察组糖皮质激素、抗生素和侵袭性操作比例分别为52.08%、79.17%和81.25%,均显著高于对照组的8.57%、35.71%和38.57%,两组比较,差异有统计学意义(P<0.05).结论:重型肝炎患者易并发肺部真菌感染,主要与应用糖皮质激素、抗生素和侵袭性操作等有关.临床中应对重型肝炎患者采取积极的防御措施,以预防和减少肺部真菌感染的发生.

AIM: To investigate the predisposing factors and preventive measures of the patients with severe hepatitis and pulmonary fungal infection. METHODS:A total of 48 cases with severe hepatitis patients and pulmonary fungal infection were selected as the observation group, and 70 cases severe hepatitis patients without pulmonary fungal infection were selected as the control group. The sugar cortical hormone, antibiotics and invasive operation application of two groups were observed. RESULTS:The sugar cortical hormone, antibiotics and invasion operation proportion in observation group were 52. 08%, 79. 17% and 81.25%, respectively, which were significantly higher than those in the control group ( 8. 57%, 35. 71% and 38. 57%) , and the difference was statistically significant ( P<0. 05 ) . CONCLU?SION: The pulmonary fungal infection and severe hepatitis were mainly related with the application of sugar cortical hormone, antibiotics and invasive operation. The clinical aggressive defensive measures should be applied to severe hepatitis patients, in order to prevent and reduce the incidence of pulmonary fungal infection.