血液透析联合血液灌流抢救重度有机磷农药中毒的临床效果研究

Clinical effect of hemodialysis combined with blood perfusion in the treatment of severe organophosphorus pesticide poisoning

目的:观察和分析有机磷农药中毒患者采用血液透析联合血液灌流联合进行抢救治疗的临床疗效.方法:选取2013-05/2014-05我院收治的重度有机磷农药中毒患者80例作为研究对象,随机分成研究组(n=40)和对照组(n=40).两组患者入院后均进行常规治疗,对照组患者在常规治疗的基础上加用血液灌流治疗,研究组患者在对照组的治疗基础上加用血液透析治疗.观察并比较两组患者的临床治疗效果.结果:经积极的抢救治疗后,研究组患者的治愈率为97.5%,显著高于对照组的治愈率(85.0%),差异具有统计学意义(P<0.05).结论:对重度有机磷农药中毒患者采用血液透析联合血液灌流进行治疗具有良好的临床疗效,值得推广应用.

AIM: To observe and analyze the clinical effect of hemodialysis combined with blood perfusion in the treatment of severe organophosphorus pesticide poisoning. METHODS: A totalof 80 patients with severe organic phosphorus pesticide in our hospital from May 2013 to May 2014 were collected in clinical study,and all patients were randomly divided into study group and control group,with 40 cases in each group. Patients in both groups after admission were given routine treatment. Additionally, hemoperfusion was given to the control group on the basis of conventional therapy and hemodialysis was used in the study group on the basis of the control group?s treatment. The clinical therapeutic effect of the two groups was observed and compared. RESULTS:The cure rate of the study group after treatment was 97. 5%, which was significantly higher than that of the control group ( 85%) , and the difference was statistically significant( P<0. 05 ) . CONCLUSION: The hemodialysis treatment combined with blood perfusion have a good clinical efficacy in patients with severe organophosphorus pesticide poisoning, which is worthy of popularization and application.