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和肽素在临床危急重症中的应用进展 被引量：6

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摘要 和素肽(copeptin)是精氨酸加压素前体的羧基肽部分,与精氨酸加压素等摩尔释放,稳定性好、方便检测,可作为精氨酸加压素的替代物用于临床检测.近年研究发现,和肽素作为一种新的生物标记物,在多种疾病的早期诊断、病情评估以及预后评价方面具有重要的临床价值.本研究对和肽素在常见急危重症中的临床应用及价值作以综述.
作者 沈鹏
机构地区 天津市第一中心医院急诊科
出处 《转化医学电子杂志》 2015年第8期125-127,共3页 E-Journal of Translational Medicine
基金 天津市卫生局科技基金(2013KY06)
关键词 和肽素 临床危急重症 应用进展
分类号 R459.7 [医药卫生—急诊医学]
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参考文献30

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二级参考文献38

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共引文献148

同被引文献65

  • 1陈灏珠.心房颤动诊断与治疗的进展和展望[J].中国实用内科杂志：临床前沿版,2006,26(1):82-85. 被引量：44
  • 2张金男,高宇飞,赵丛海,王立坤,赵勇.神经外科术后中枢性尿崩症ADH变化曲线及其临床意义[J].吉林大学学报（医学版）,2006,32(6):1087-1090. 被引量：4
  • 3无.儿童社区获得性肺炎管理指南（试行）（下）[J].中华儿科杂志,2007,45(3):223-230. 被引量：207
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  • 5KATAN M, MORGENTHALER N, WIDMER I, et al. Copeptin, a stable peptide derived from the vasopressin precursor, correlates with the individual stl~ss level[J]. Neuro Endocrinol Lett, 2008, 29(3) : 341 -346.
  • 6BOECK L, EGGIMANN P, SMYRNIOS N, et al. The Sequential Organ Failure Assessment score and copeptin for predicting surviv- al in ventilator- associated pneumonia[J]. J Crit Care 2012, 27 (5) : 523.
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  • 9NICKEL C H, BINGISSER R, MORGENTHALER N G. The role of copeptin as a diagnostic and prognostic biomarker for risk strati- fication in the emergency department[J]. BMC Med, 2012, 10: 7.
  • 10BOLIGNANO D, CABASSI A, FIACCADOR1 E, et al. Copeptin ( CTproAVP), a new tool for understanding the role of vasopressin in pathophysiology [ J ]. Clin Chem Lab Med, 2014, 52 (10) : 1447 - 1456.

引证文献6

二级引证文献42

转化医学电子杂志
2015年 第8期

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