婴幼儿孤独症早期筛查及其影响因素

Early screening and influencing factors of infantile autism

目的探讨婴幼儿孤独症初步筛查情况及其影响因素,为孤独症的早期干预提供依据。方法 2013年1—6月,采用婴幼儿沟通与象征性行为发展量表（CSBS）对深圳市公明社区1 845例18~24月龄的婴幼儿进行孤独症筛查,分析社交、语言及象征性行为,并将筛查总分可疑的儿童分别利用单因素和多因素logistic回归方法分析其影响因素。结果社交行为可疑103例,语言可疑189例,象征性行为可疑103例,总分可疑135例,阳性率分别为5.58%、10.24%、5.58%、7.32%。对总分可疑的135例进行多因素logistic回归分析,结果显示,非早产和父亲的文化程度是保护性因素,差异有统计学意义（P〈0.05）。结论深圳市公明社区孤独症阳性率较高,早产和父亲文化程度是影响因素。

[Objective]To explore the preliminary screening results and influencing factors of infantile autism,provide the basis for early intervention of autism. [Methods]1845 children aged 18-24 months old in Gongming Community of Shenzhen City were recruited in this study from January to June in 2013. The Communication and Symbolic Behavior Scale-Developmental Profile（CSBS）was adopted in the screening,to investigate the social intercourse,language and symbolic behavior. The infants with suspicious results were analyzed by single factor regression and multiple logistic regression methods,to investigate the influencing factors.[Results]There were 103 cases of suspicious results in social intercourse,189 cases of suspicious results in language,103 cases of suspicious results in symbolic behavior,and 135 cases of suspicious results in total scores,which the positive rate was5.58%,10.24%,5.58% and 7.32%,respectively. The multiple logistic regression in 135 cases of suspicious results in total scores showed that non-premature labor and father＇s education level were the protective factors, and the difference was statistically significant（P〈0.05）.[Conclusion]The positive rate of autism is high in Gongming Community of Shenzhen City,and the influencing factors include premature and father＇s education level.