常用美白祛斑中药抗氧化活性比较

The Comparision of Antioxidant Activities on Akin-whitening and Anti-freckling chinese herbs

目的:研究七种中药的体外抗氧化作用,比较体外清除自由基能力,来指导这些中药在美白祛斑方面的应用。方法:药材粉碎,无水乙醇作溶剂,超声提取各中药材,采用DPPH·法测定各提取液清除自由基的活性并以IC50的值作为评定各中药材体外抗氧化能力的大小。结果:白术、防风、白芷、紫草、牡丹皮、地黄、当归的IC50值分别为11.60 g·L-1、4.17 g·L-1、18.94 g·L-1、21.60 g·L-1、4.17 g·L-1、40.30 g·L-1、8.23 g·L-1,表明抗氧化活性:防风=牡丹皮>当归>白术>白芷>紫草>地黄:结论:七种中药都具有抗氧化活性能力,其中防风和牡丹皮醇提液抗氧化活性能力最强,地黄醇提液抗氧化活性能力最弱。

Objective：To explore the antioxidant activities on 7 kinds of skin-whitening and anti-freckling chinese herbs. Compare the a- bility of scavenging free radicals in vitro, to guide the application of the traditional Chinese medicine in white spot. Methods ： crushing the herbs and anhydrous ethanol as solvent, ultrasonic extraction various Chinese medicinal materials, determine the extract by DPPH · method, the activity of scavenging free radicals and IC50 value as the evaluation of each the size of the Chinese herbal medicine in vitro antioxidant capacity. Results：the IC50 of Atractylodes is 11.60 g · L-1 , Radix Sileris is 4.17 g 2L-1 , Dahurian Angelica is 18.94 g ·L-1 ,Lithospermum is 21.60 mg · mL-1 Cortex Moutan is 4.17 g · L-1 Rehmannia Glutinosa Libosch is 40.30 g · L-1 and Chinese Angelica is 8.23 g · L-l, respectively, that means the antioxidant activity of these seven chinese herbs is Radix Sileris = Cortex Moutan 〉 Chinese Angelica 〉 Atractylodes 〉 Dahurian Angelica 〉 Lithospermum 〉 Digitalis. Conclusion ： seven kinds of chinese herbs has different ability of removing Free radicals. In sum, Radix Sileris and Cortex Moutan alcohol extract has the strongest ability of remo- ving free radicals, Rehmannia Glutinosa Libosch extract is weakest.