摘要
目的:评价针灸治疗失眠的临床疗效。方法:应用计算机和手工检索数据库中关于针灸治疗失眠的临床研究文献,选择符合要求的随机对照试验、临床对照试验文献,按照循证医学系统评价方法,评价纳入研究的文献质量,并用改良后Jadad评分量表评分,运用RevM an5.3.5软件进行系统分析。结果:本次研究共纳入10篇文献,共计757例失眠患者。分析显示针灸疗法与药物疗法睡眠质量比较,差异有统计学意义[MD=-1.14,95%CI(-2.05,-0.23),P=0.01]。针灸疗法与药物疗法总有效率比较,差异有统计学意义[Z=6.14,OR=5.24,95%CI=(3.09,8.89),P<0.000 01]。结论:针灸治疗失眠症临床有效,且较常规药物有一定的优势,但由于研究中纳入的文献质量普遍不高,尚需要更多严格的随机对照试验来进一步验证。
Objective: To assess the therapeutic effect of acupuncture on insomnia. Methods: Application of computer and manual-a searchable database of clinical research literature about acupuncture and moxibustion treatment of insomnia,selection the randomized controlled trial( RCT) and controlled clinical trials( CCT) literature which conformed to the requirement. And then used the modified Jadad score rating scale,the data were statistically analyzed with a special software RevM an5. 3. 5. Results: Ten papers including 757 patients met the enrolled criteria. Meta-analysis derived: the difference in sleep quality,the acupuncture treatment compared with drug control,was statistically significant[MD =- 1. 14,95% CI(- 2. 05,- 0. 23),P = 0. 01]. The difference in efficiency,the acupuncture treatment compared with drug control,was statistically significant[Z = 6. 14,OR = 5. 24,95% CI =( 3. 09,8. 89),P〈 0. 000 01]. Conclusion Acupuncture is effective for insomnia,and compare with drugs it has certain advantages. However,because of lower methodological quality of all the trials,it still need more rigorous randomized controlled trials to the further verification.
出处
《中医学报》
CAS
2015年第10期1511-1514,共4页
Acta Chinese Medicine
基金
国家自然科学基金项目(81173335)
关键词
失眠
针灸疗法
META分析
insomnia
acupuncture therapy
Meta-analysis